Raymond Mphakamisi Mhlaba (12 February 1920 – 20 February 2005) was an anti-apartheid activist, Communist and leader of the African National Congress (ANC) also as well the first premier of the Eastern Cape.

Mhlaba spent 25 years of his life in prison. Well known for being sentenced, along with Nelson Mandela, Govan Mbeki, Walter Sisulu and others in the Rivonia Trial, he was an active member of the ANC and the South African Communist Party (SACP) all his adult life. His kindly manner brought him the nickname “Oom Ray”.